Neuroscience

Pfizer is taking a bold leadership approach that will evolve from dealing with symptoms to modifying diseases, where scientifically feasible. As a result, Pfizer has new approaches to attack Alzheimer’s disease, schizophrenia and other feared conditions. For anxiety, sleep disorders, and neuropathic pain, we continue to expand inquiry into alpha-2-delta binding site agents.


Conditions


Alzheimer´s Disease
A progressive disorder characterized by the loss of personal and factual memory and a decline in cognitive ability, it is often accompanied by a sense of disorientation. It is only in the last few years that researchers have truly come to understand the causes of Alzheimer's, its effect on the brain, and how and why it kills brain cells, causing the devastation of many families, and changing friends and loved ones into completely different people. Coupled with this is the wider appreciation and understanding of a disease no longer considered to be just a normal part of the aging process. Despite this growing knowledge, Alzheimer's remains one of the world's most undiagnosed diseases, with only an estimated third of the world's Alzheimer's sufferers (estimated to be 18 million people) receiving treatment. Through years of scientific research to help gain understanding, the Neuroscience team now has a multitude of potential treatments for Alzheimer's in research and development. Coupled with this are the team's efforts to develop an effective tool to detect Alzheimer's early and if possible before onset of the disease. Pfizer's commitment to finding new medicines to treat Alzheimer's was cemented in 2006 with the acquisition of Rinat Bioscience, and partnership with Transtech Pharma.

Depression
Prolonged feelings of sadness, despair and discouragement often accompanied by low self esteem, guilt and self reproach, which can also lead to withdrawal from interpersonal contact as well as eating and sleeping disorders.

Epilepsy
A disorder of the nervous system resulting from electrical activity in the brain, and characterized by seizures.

General Anxiety Disorder
An uncontrollable worry about everyday things which can often impair a patient´s normal daily functioning.

Insomnia
The persistent inability to fall asleep or remain asleep throughout the night.

Bipolar Disorder, Manic Depressive Illness
A major mood disorder in which patients cycle between periods of depression or mania.

Panic Disorder
An anxiety disorder characterized by short but disabling periods of intense fear and worry, often accompanied by rapid heart beat and dizziness.

Schizophrenia
A severe mental disorder often characterized by hallucinations, delusions, and changes in outlook and personality.

Smoking Cessation
Aid to help people quit smoking.